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Mammalian Orthoreovirus Particles Induce and Are Recruited into Stress Granules at Early Times Postinfection
Infection with many mammalian orthoreovirus (MRV) strains results in shutoff of host, but not viral, protein synthesis via protein kinase R (PKR) activation and phosphorylation of translation initiation factor eIF2α. Following inhibition of protein synthesis, cellular mRNAs localize to discrete stru...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772771/ https://ncbi.nlm.nih.gov/pubmed/19710141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01239-09 |
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