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Structural and Functional Analysis of Hepatitis C Virus Strain JFH1 Polymerase
The hepatitis C virus (HCV) isolate JFH1 represents the only cloned wild-type sequence capable of efficient replication in cell culture, as well as in chimpanzees. Previous reports have pointed to the viral polymerase NS5B as a major determinant for efficient replication of this isolate. To understa...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2772714/ https://ncbi.nlm.nih.gov/pubmed/19740982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01008-09 |
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