Structural and Functional Analysis of Hepatitis C Virus Strain JFH1 Polymerase

The hepatitis C virus (HCV) isolate JFH1 represents the only cloned wild-type sequence capable of efficient replication in cell culture, as well as in chimpanzees. Previous reports have pointed to the viral polymerase NS5B as a major determinant for efficient replication of this isolate. To understa...

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Detalhes bibliográficos
Main Authors: Simister, Philip, Schmitt, Melanie, Geitmann, Matthis, Wicht, Oliver, Danielson, U. Helena, Klein, Rahel, Bressanelli, Stéphane, Lohmann, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Structure and Assembly
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772714/
https://ncbi.nlm.nih.gov/pubmed/19740982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01008-09
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