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The Phthalocyanine Prototype Derivative Alcian Blue Is the First Synthetic Agent with Selective Anti-Human Immunodeficiency Virus Activity Due to Its gp120 Glycan-Binding Potential

Alcian Blue (AB), a phthalocyanine derivative, is able to prevent infection by a wide spectrum of human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus strains in various cell types [T cells, (co)receptor-transfected cells, and peripheral blood mononuclear cells]. Wit...

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Autors principals: François, Katrien O., Pannecouque, Christophe, Auwerx, Joeri, Lozano, Virginia, Pérez-Pérez, Maria-Jésus, Schols, Dominique, Balzarini, Jan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772342/
https://ncbi.nlm.nih.gov/pubmed/19721061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00811-09
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