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Influence of Inoculum Size and Marbofloxacin Plasma Exposure on the Amplification of Resistant Subpopulations of Klebsiella pneumoniae in a Rat Lung Infection Model

We tested the hypothesis that the bacterial load at the infection site could impact considerably on the pharmacokinetic/pharmacodynamic (PK/PD) parameters of fluoroquinolones. Using a rat lung infection model, we measured the influence of different marbofloxacin dosage regimens on selection of resis...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kesteman, Anne-Sylvie, Ferran, Aude A., Perrin-Guyomard, Agnès, Laurentie, Michel, Sanders, Pascal, Toutain, Pierre-Louis, Bousquet-Mélou, Alain
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology (ASM) 2009
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772313/
https://ncbi.nlm.nih.gov/pubmed/19738020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00608-09
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