Interrogating the Bioactive Pharmacophore of the Latrunculin Chemotype by Investigating the Metabolites of Two Taxonomically Unrelated Sponges

This study involved a campaign to isolate and study additional latrunculin analogs from two taxonomically unrelated sponges, Cacospongia mycofijiensis and Negombata magnifica. A total of 13 latrunculin analogs were obtained by four different ways, reisolation (1–4), our repository (5–6), new derivat...

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Autori principali: Amagata, Taro, Johnson, Tyler A., Cichewicz, Robert H., Tenney, Karen, Mooberry, Susan L., Media, Joseph, Edelstein, Matthew, Valeriote, Frederick A., Crews, Phillip
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772107/
https://ncbi.nlm.nih.gov/pubmed/18942825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm8008585
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