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The Sponge-Derived Fijianolide Polyketide Class: Further Evaluation of Their Structural and Cytotoxicity Properties

The sponge derived polyketide macrolides fijianolides A (1) and B (2) (a.k.a. isolaulimalide and laulimalide) have taxol-like microtubule-stabilizing activity and the latter exhibits potent cytotoxicity. Insight on the biogeographical and phenotypic variations of Cacospongia mycofijiensis is present...

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Detalhes bibliográficos
Main Authors: Johnson, Tyler A., Tenney, Karen, Cichewicz, Robert H., Morinaka, Brandon I., White, Kimberly N., Amagata, Taro, Subramanian, Balanehru, Media, Joseph, Mooberry, Susan L., Valeriote, Frederick A., Crews, Phillip
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772109/
https://ncbi.nlm.nih.gov/pubmed/17622130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm070410z
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