Therapeutic efficacy of soluble receptor activator of nuclear factor-κB-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma

PURPOSE: Osteosarcoma is the most frequent primary bone tumor that develops mainly during youth, the median age of diagnosis being 18 years old. Despite improvement in osteosarcoma treatment, survival rate is only 30% after 5 years for patients with pulmonary metastases at diagnosis. This warrants e...

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Main Authors:	Lamoureux, François, Picarda, Gaëlle, Rousseau, Julie, Gourden, Clothilde, Battaglia, Séverine, Charrier, Céline, Pitard, Bruno, Heymann, Dominique, Rédini, Françoise
Format:	Artigo
Language:	Inglês
Published:	American Association for Cancer Research, Inc. 2008
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2772022/ https://ncbi.nlm.nih.gov/pubmed/18852142 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0497
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Therapeutic efficacy of soluble receptor activator of nuclear factor-κB-Fc delivered by nonviral gene transfer in a mouse model of osteolytic osteosarcoma

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