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IgG-Paraoxonase-1 Fusion Protein for Targeted Drug Delivery Across the Human Blood-Brain Barrier

Paraoxonase (PON)-1 is the most potent human protein with organophosphatase activity against organophosphate (OP) toxins. OP compounds readily cross the blood-brain barrier (BBB), and have lethal mechanisms of action within the brain. The production of a brain penetrating form of human PON1, which c...

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Detaylı Bibliyografya
Asıl Yazarlar: Boado, Ruben J., Zhang, Yun, Zhang, Yufeng, Wang, Yuntao, Pardridge, William M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771892/
https://ncbi.nlm.nih.gov/pubmed/19434854
Etiketler: Etiketle
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