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Meat and heterocyclic amine intake, smoking, NAT1 and NAT2 polymorphisms and colorectal cancer risk in the Multiethnic Cohort Study

BACKGROUND: N-acetyltransferases (NAT) 1 and 2 are polymorphic enzymes catalyzing the metabolic activation of heterocyclic amines (HCA). We investigated the modifying effects of NAT1 and NAT2 polymorphisms on the association of meat consumption, HCA intake, and smoking with colorectal cancer (CRC) r...

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Detalhes bibliográficos
Main Authors: Nöthlings, Ute, Yamamoto, Jennifer F., Wilkens, Lynne R., Murphy, Suzanne P., Park, Song-Yi, Henderson, Brian E., Kolonel, Laurence N., Marchand, Loïc Le
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771770/
https://ncbi.nlm.nih.gov/pubmed/19549810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-08-1218
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