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Comparative analyses of chromosome alterations in soft-tissue metastases within and across patients with castration-resistant prostate cancer

Androgen deprivation is the mainstay of therapy for progressive prostate cancer. Despite initial and dramatic tumor inhibition, most men eventually fail therapy and die of metastatic castration-resistant (CR) disease. Here, we characterize the profound degree of genomic alteration found in CR tumors...

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Detalhes bibliográficos
Main Authors: Holcomb, Ilona N., Young, Janet M., Coleman, Ilsa M., Salari, Keyan, Grove, Douglas I., Hsu, Li, True, Lawrence D., Roudier, Martine P., Morrissey, Colm M., Higano, Celestia S., Nelson, Peter S., Vessella, Robert L., Trask, Barbara J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771763/
https://ncbi.nlm.nih.gov/pubmed/19773449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-3810
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