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Potential Benefits of Sequential Inhibitor-Mutagen Treatments of RNA Virus Infections
Lethal mutagenesis is an antiviral strategy consisting of virus extinction associated with enhanced mutagenesis. The use of non-mutagenic antiviral inhibitors has faced the problem of selection of inhibitor-resistant virus mutants. Quasispecies dynamics predicts, and clinical results have confirmed,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771356/ https://ncbi.nlm.nih.gov/pubmed/19911056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000658 |
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