Efficient Virus Extinction by Combinations of a Mutagen and Antiviral Inhibitors

The effect of combinations of the mutagenic base analog 5-fluorouracil (FU) and the antiviral inhibitors guanidine hydrochloride (G) and heparin (H) on the infectivity of foot-and-mouth disease virus (FMDV) in cell culture has been investigated. Related FMDV clones differing up to 10(6)-fold in rela...

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Detalhes bibliográficos
Main Authors: Pariente, Nonia, Sierra, Saleta, Lowenstein, Pedro R., Domingo, Esteban
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Recombination and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114544/
https://ncbi.nlm.nih.gov/pubmed/11559805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9723-9730.2001
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