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Zebrafish chemical screening reveals an inhibitor of Dusp6 that expands cardiac cell lineages
The dual specificity phosphatase 6 (Dusp6) functions as a feedback regulator of fibroblast growth factor (FGF) signaling to limit the activity of extracellular signal regulated kinase (ERK) 1 and 2. We have identified a small molecule inhibitor of Dusp6, (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dih...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771339/ https://ncbi.nlm.nih.gov/pubmed/19578332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.190 |
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