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Quantitative measurement of zinc secretion from pancreatic islets with high temporal resolution using droplet-based microfluidics

We assayed glucose-stimulated insulin secretion (GSIS) from live, murine islets of Langerhans in microfluidic devices by the downstream formation of aqueous droplets. Zinc ions, which are co-secreted with insulin from β-cells, were quantitatively measured from single islets with high temporal resolu...

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Main Authors: Easley, Christopher J., Rocheleau, Jonathan V., Head, W. Steven, Piston, David W.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771320/
https://ncbi.nlm.nih.gov/pubmed/19874061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac9017692
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