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Mutational analysis of the cytoplasmic domain of CEACAM1-4L in humanized mammary glands reveals key residues involved in lumen formation: stimulation by Thr-457 and inhibition by Ser-461
CEACAM1 (carcinoembryonic antigen-related cell adhesion molecule 1), a type I transmembrane glycoprotein involved in cell-cell adhesion, undergoes extensive alternative splicing, resulting in isoforms with 1–4 Ig-like extracellular domains (ECDs) with either long or short cytoplasmic tails. We have...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771115/ https://ncbi.nlm.nih.gov/pubmed/19146852 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2008.12.015 |
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