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Direct Interaction of Tumor Suppressor CEACAM1 with Beta Catenin: Identification of Key Residues in the Long Cytoplasmic Domain

CEACAM1-4L (carcinoembryonic antigen cell adhesion molecule 1, with 4 extracellular Ig-like domains and a long, 71 amino acid cytoplasmic domain) is expressed in epithelial cells and activated T-cells, but is down-regulated in most epithelial cell cancers and T-cell leukemias. A highly conserved seq...

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Main Authors: Jin, Lan, Li, Yun, Chen, Charng-Jui, Sherman, Mark A., Le, Keith, Shively, John E.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745821/
https://ncbi.nlm.nih.gov/pubmed/18445773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3181/0712-RM-352
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