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Role of calpain-9 and PKC-δ in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells

CEACAM1-4S (carcinoembryonic antigen-related cell adhesion molecule 1) is a type I membrane protein with a short (12 amino acid) cytoplasmic tail. Wild type CEACAM1-4S transfected MCF7 cells form glands with lumena when grown in 3D culture, while null mutations of two putative phosphorylation sites...

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Main Authors: Chen, Charng-Jui, Nguyen, Tung, Shively, John E.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2868383/
https://ncbi.nlm.nih.gov/pubmed/19909740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2009.11.001
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