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Low Oxygen Enhances Primitive and Definitive Neural Stem Cell Colony Formation by Inhibiting Distinct Cell Death Pathways

Neural stem cells (NSCs) can be derived from single mouse embryonic stem cells (ESCs) in the absence of instructive factors. Clonal primitive NSC (pNSC) colonies are formed first, and then give rise to clonal, fibroblast growth factor-dependent definitive neural stem cells (dNSCs). We tested low-oxy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Clarke, Laura, van der Kooy, Derek
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771103/
https://ncbi.nlm.nih.gov/pubmed/19544448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.96
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