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Embryonic stem cells assume a primitive neural stem cell fate in the absence of extrinsic influences

The mechanisms governing the emergence of the earliest mammalian neural cells during development remain incompletely characterized. A default mechanism has been suggested to underlie neural fate acquisition; however, an instructive process has also been proposed. We used mouse embryonic stem (ES) ce...

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Detalhes bibliográficos
Main Authors: Smukler, Simon R., Runciman, Susan B., Xu, Shunbin, van der Kooy, Derek
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063536/
https://ncbi.nlm.nih.gov/pubmed/16390999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200508085
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