α-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

During blood vessel development, vascular smooth muscle cells (vSMCs) and pericytes (PCs) are recruited to nascent vessels to stabilize them and to guide further vessel remodelling. Here, we show that loss of the focal adhesion (FA) protein α-parvin (α-pv) in mice leads to embryonic lethality due to...

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Main Authors: Montanez, Eloi, Wickström, Sara A, Altstätter, Johannes, Chu, Haiyan, Fässler, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771098/
https://ncbi.nlm.nih.gov/pubmed/19798050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.295
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