α-parvin controls vascular mural cell recruitment to vessel wall by regulating RhoA/ROCK signalling

During blood vessel development, vascular smooth muscle cells (vSMCs) and pericytes (PCs) are recruited to nascent vessels to stabilize them and to guide further vessel remodelling. Here, we show that loss of the focal adhesion (FA) protein α-parvin (α-pv) in mice leads to embryonic lethality due to...

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Huvudupphovsmän: Montanez, Eloi, Wickström, Sara A, Altstätter, Johannes, Chu, Haiyan, Fässler, Reinhard
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2009
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2771098/
https://ncbi.nlm.nih.gov/pubmed/19798050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.295
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