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Neuroligin-1 performs neurexin-dependent and neurexin-independent functions in synapse validation
Postsynaptic neuroligins are thought to perform essential functions in synapse validation and synaptic transmission by binding to, and dimerizing, presynaptic α- and β-neurexins. To test this hypothesis, we examined the functional effects of neuroligin-1 mutations that impair only α-neurexin binding...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2771087/ https://ncbi.nlm.nih.gov/pubmed/19730411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.249 |
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