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Kinetics of Association and Dissociation of HIV-1 Reverse Transcriptase Subunits

The biologically active form of HIV-1 reverse transcriptase is the p66/p51 heterodimer. The process of maturation of the heterodimer from precursor proteins is poorly understood. Previous studies indicated that association of p66 and p51 is very slow. Three techniques, a pre-steady-state activity as...

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Detalhes bibliográficos
Main Authors: Venezia, Carl F., Meany, Brendan J., Braz, Valerie A., Barkley, Mary D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770954/
https://ncbi.nlm.nih.gov/pubmed/19715314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9010495
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