Rabbit Polyclonal Anti-Mouse Thymocyte Globulin Administration Alters Dendritic Cell Profile and Function in NOD Mice to Suppress Diabetogenic Responses

Anti-mouse thymocyte globulin (mATG) prevents, as well as reverses, type-1 diabetes (T1D) in NOD mice, through mechanisms involving modulation of the immunoregulatory activities of T lymphocytes. Dendritic cells (DC) play a pivotal role in the generation of T cell responses, including those relevant...

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Autori principali: Huang, Yanfei, Parker, Matthew, Xia, Changqing, Peng, Ruihua, Wasserfall, Clive, Clarke, Tracy, Wu, Lizhen, Chowdhry, Tayseer, Campbell-Thompson, Martha, Williams, John, Clare-Salzler, Michael, Atkinson, Mark A., Womer, Karl L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770841/
https://ncbi.nlm.nih.gov/pubmed/19342635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0713269
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