The Tyrphostin Agent AG490 Prevents and Reverses Type 1 Diabetes in NOD Mice

BACKGROUND: Recent studies in the NOD (non-obese diabetic) mouse model of type 1 diabetes (T1D) support the notion that tyrosine kinase inhibitors have the potential for modulating disease development. However, the therapeutic effects of AG490 on the development of T1D are unknown. MATERIALS AND MET...

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Main Authors: Davoodi-Semiromi, Abdoreza, Wasserfall, Clive H., Xia, Chang Qing, Cooper-DeHoff, Rhonda M., Wabitsch, Martin, Clare-Salzler, Michael, Atkinson, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351395/
https://ncbi.nlm.nih.gov/pubmed/22615750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036079
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