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Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences

Cystic fibrosis (CF) is caused by mutated CF transmembrane conductance regulator (CFTR) and is characterized by robust airway inflammation and accumulation of apoptotic cells. Phagocytosis of apoptotic cells (efferocytosis) is a pivotal regulator of inflammation, because it prevents postapoptotic ne...

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Bibliografiset tiedot
Päätekijät: Vandivier, R. William, Richens, Tiffany R., Horstmann, Sarah A., deCathelineau, Aimee M., Ghosh, Moumita, Reynolds, Susan D., Xiao, Yi-Qun, Riches, David W., Plumb, Jonathan, Vachon, Eric, Downey, Gregory P., Henson, Peter M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770781/
https://ncbi.nlm.nih.gov/pubmed/19633071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00030.2009
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