Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences

Cystic fibrosis (CF) is caused by mutated CF transmembrane conductance regulator (CFTR) and is characterized by robust airway inflammation and accumulation of apoptotic cells. Phagocytosis of apoptotic cells (efferocytosis) is a pivotal regulator of inflammation, because it prevents postapoptotic ne...

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Detalhes bibliográficos
Main Authors: Vandivier, R. William, Richens, Tiffany R., Horstmann, Sarah A., deCathelineau, Aimee M., Ghosh, Moumita, Reynolds, Susan D., Xiao, Yi-Qun, Riches, David W., Plumb, Jonathan, Vachon, Eric, Downey, Gregory P., Henson, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770781/
https://ncbi.nlm.nih.gov/pubmed/19633071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00030.2009
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