Acute and Chronic Alcohol Exposure Impair the Phagocytosis of Apoptotic Cells and Enhance the Pulmonary Inflammatory Response

BACKGROUND: Alcohol abuse increases the risk for acute respiratory distress syndrome (ARDS). Efferocytosis, the clearance of apoptotic cells, is important in the resolution of inflammation and is regulated by RhoA and rho kinase (ROCK) activation. The effects of alcohol on pulmonary Rho pathway acti...

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Hauptverfasser: Boé, Darren M., Richens, Tiffany R., Horstmann, Sarah A., Burnham, Ellen L., Janssen, William J., Henson, Peter M., Moss, Marc, Vandivier, R. William
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950894/
https://ncbi.nlm.nih.gov/pubmed/20608904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01259.x
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