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Acute and Chronic Alcohol Exposure Impair the Phagocytosis of Apoptotic Cells and Enhance the Pulmonary Inflammatory Response

BACKGROUND: Alcohol abuse increases the risk for acute respiratory distress syndrome (ARDS). Efferocytosis, the clearance of apoptotic cells, is important in the resolution of inflammation and is regulated by RhoA and rho kinase (ROCK) activation. The effects of alcohol on pulmonary Rho pathway acti...

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Bibliografiske detaljer
Main Authors: Boé, Darren M., Richens, Tiffany R., Horstmann, Sarah A., Burnham, Ellen L., Janssen, William J., Henson, Peter M., Moss, Marc, Vandivier, R. William
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950894/
https://ncbi.nlm.nih.gov/pubmed/20608904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1530-0277.2010.01259.x
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