The Drosophila HP1 homologue Rhino is required for transposon silencing and piRNA production by dual strand clusters

piRNAs silence transposons and maintain genome integrity during germ-line development. In Drosophila, transposon-rich heterochromatic clusters encode piRNAs either on both genomic strands (dual-strand clusters) or predominantly one genomic strand (uni-strand clusters). Primary piRNAs derived from th...

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Hauptverfasser: Klattenhoff, Carla, Xi, Hualin, Li, Chengjian, Lee, Soohyun, Xu, Jia, Khurana, Jaspreet S., Zhang, Fan, Schultz, Nadine, Koppetsch, Birgit S., Nowosielska, Anetta, Seitz, Herve, Zamore, Phillip D., Weng, Zhiping, Theurkauf, William E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770713/
https://ncbi.nlm.nih.gov/pubmed/19732946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.07.014
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