CpG-depleted promoters harbor tissue-specific transcription factor binding signals—implications for motif overrepresentation analyses

Motif overrepresentation analysis of proximal promoters is a common approach to characterize the regulatory properties of co-expressed sets of genes. Here we show that these approaches perform well on mammalian CpG-depleted promoter sets that regulate expression in terminally differentiated tissues...

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Bibliografiska uppgifter
Huvudupphovsmän: Roider, Helge G., Lenhard, Boris, Kanhere, Aditi, Haas, Stefan A., Vingron, Martin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Computational Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770660/
https://ncbi.nlm.nih.gov/pubmed/19736212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp682
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