A real-time fluorescence method for enzymatic characterization of specialized human DNA polymerases

Specialized DNA polymerases are involved in DNA synthesis during base-excision repair and translesion synthesis across a wide range of chemically modified DNA templates. Notable features of these enzymes include low catalytic efficiency, low processivity and low fidelity. Traditionally, in vitro stu...

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Detalhes bibliográficos
Main Authors: Dorjsuren, Dorjbal, Wilson, David M., Beard, William A., McDonald, John P., Austin, Christopher P., Woodgate, Roger, Wilson, Samuel H., Simeonov, Anton
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770649/
https://ncbi.nlm.nih.gov/pubmed/19684079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp641
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