Solution and Crystal Molecular Dynamics Simulation Study of m4-Cyanovirin-N Mutants Complexed with Di-Mannose

Cyanovirin-N (CVN) is a highly potent anti-HIV carbohydrate-binding agent that establishes its microbicide activity through interaction with mannose-rich glycoprotein gp120 on the virion surface. The m4-CVN and P51G-m4-CVN mutants represent simple models for studying the high-affinity binding site,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Vorontsov, Ivan I., Miyashita, Osamu
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The Biophysical Society 2009
विषय:
Protein
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770623/
https://ncbi.nlm.nih.gov/pubmed/19883596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.011
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