Helical Conformation of the SEVI Precursor Peptide PAP(248-286), a Dramatic Enhancer of HIV Infectivity, Promotes Lipid Aggregation and Fusion

In previous in vivo studies, amyloid fibers formed from a peptide ubiquitous in human seminal fluid (semen-derived enhancer of viral infection (SEVI)) were found to dramatically enhance the infectivity of the HIV virus (3–5 orders of magnitude by some measures). To complement those studies, we perfo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Brender, Jeffrey R., Hartman, Kevin, Gottler, Lindsey M., Cavitt, Marchello E., Youngstrom, Daniel W., Ramamoorthy, Ayyalusamy
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2009
Pynciau:
Membrane
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770606/
https://ncbi.nlm.nih.gov/pubmed/19883590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2009.08.034
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