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Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm

The disintegration of the dystrophin-glycoprotein complex represents the initial pathobiochemical insult in Duchenne muscular dystrophy. However, secondary changes in signalling, energy metabolism and ion homeostasis are probably the main factors that eventually cause progressive muscle wasting. Thu...

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Bibliografiset tiedot
Päätekijät: Doran, Philip, Wilton, Steve D., Fletcher, Sue, Ohlendieck, Kay
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770591/
https://ncbi.nlm.nih.gov/pubmed/19132684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800441
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