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Proteomic profiling of antisense-induced exon skipping reveals reversal of pathobiochemical abnormalities in dystrophic mdx diaphragm

The disintegration of the dystrophin-glycoprotein complex represents the initial pathobiochemical insult in Duchenne muscular dystrophy. However, secondary changes in signalling, energy metabolism and ion homeostasis are probably the main factors that eventually cause progressive muscle wasting. Thu...

詳細記述

保存先:
書誌詳細
主要な著者: Doran, Philip, Wilton, Steve D., Fletcher, Sue, Ohlendieck, Kay
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770591/
https://ncbi.nlm.nih.gov/pubmed/19132684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200800441
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