Leptin interferes with 3',5'-Cyclic Adenosine Monophosphate (cAMP) signaling to inhibit steroidogenesis in human granulosa cells

BACKGROUND: Obesity has been linked to an increased risk of female infertility. Leptin, an adipocytokine which is elevated during obesity, may influence gonadal function through modulating steroidogenesis in granulosa cells. METHODS: The effect of leptin on progesterone production in simian virus 40...

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Autores principales: Lin, Qing, Poon, Song Ling, Chen, Junling, Cheng, Linan, HoYuen, Basil, Leung, Peter CK
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770482/
https://ncbi.nlm.nih.gov/pubmed/19849856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-7-115
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