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Structural and Biochemical Characterization of the Interaction between KPC-2β-Lactamase and β-Lactamase Inhibitor Protein, BLIP
KPC β-lactamases hydrolyze the “last resort” β-lactam antibiotics (carbapenems) used to treat multi-drug resistant infections, and are compromising efforts to combat life-threatening Gram-negative bacterial infections in hospitals worldwide. Consequently, the development of novel inhibitors is essen...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2769493/ https://ncbi.nlm.nih.gov/pubmed/19731932 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9007963 |
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