Identification of FGFR4-activating mutations in human rhabdomyosarcomas that promote metastasis in xenotransplanted models

Rhabdomyosarcoma (RMS) is a childhood cancer originating from skeletal muscle, and patient survival is poor in the presence of metastatic disease. Few determinants that regulate metastasis development have been identified. The receptor tyrosine kinase FGFR4 is highly expressed in RMS tissue, suggest...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: VI, James G. Taylor, Cheuk, Adam T., Tsang, Patricia S., Chung, Joon-Yong, Song, Young K., Desai, Krupa, Yu, Yanlin, Chen, Qing-Rong, Shah, Kushal, Youngblood, Victoria, Fang, Jun, Kim, Su Young, Yeung, Choh, Helman, Lee J., Mendoza, Arnulfo, Ngo, Vu, Staudt, Louis M., Wei, Jun S., Khanna, Chand, Catchpoole, Daniel, Qualman, Stephen J., Hewitt, Stephen M., Merlino, Glenn, Chanock, Stephen J., Khan, Javed
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2769177/
https://ncbi.nlm.nih.gov/pubmed/19809159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39703
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars