Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis

BACKGROUND: Gene expression profiling has distinguished sporadic breast tumour classes with genetic and clinical differences. Less is known about the molecular classification of familial breast tumours, which are generally considered to be less heterogeneous. Here, we describe molecular signatures t...

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Detalhes bibliográficos
Main Authors: Fernández-Ramires, R, Solé, X, De Cecco, L, Llort, G, Cazorla, A, Bonifaci, N, Garcia, M J, Caldés, T, Blanco, I, Gariboldi, M, Pierotti, M A, Pujana, M A, Benítez, J, Osorio, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768459/
https://ncbi.nlm.nih.gov/pubmed/19826428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605275
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