Down-regulation of frizzled-7 expression decreases survival, invasion and metastatic capabilities of colon cancer cells

BACKGROUND: The canonical Wnt signalling pathway is activated in most sporadic colorectal cancers (CRCs). We previously reported that FZD7 functions as a receptor for the canonical Wnt signalling pathway in colon cancer cells. METHODS AND RESULTS: In this study, we examined the function of FZD7 in s...

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Autors principals: Ueno, K, Hazama, S, Mitomori, S, Nishioka, M, Suehiro, Y, Hirata, H, Oka, M, Imai, K, Dahiya, R, Hinoda, Y
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
Matèries:
Molecular Diagnostics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768449/
https://ncbi.nlm.nih.gov/pubmed/19773752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605307
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