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Neuroprotective Effects of Inositol 1,4,5-Trisphosphate Receptor C-Terminal Fragment in a Huntington's Disease Mouse Model

Huntington's disease (HD) is a dominantly inherited, progressive neurodegenerative disease caused by an expanded polyglutamine tract in huntingtin protein (Htt). Medium spiny striatal neurons (MSNs) are primarily affected in HD. Mutant huntingtin protein (Htt(exp)) specifically binds to and act...

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Sonraí Bibleagrafaíochta
Main Authors: Tang, Tie-Shan, Guo, Caixia, Wang, Hongyu, Chen, Xi, Bezprozvanny, Ilya
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768402/
https://ncbi.nlm.nih.gov/pubmed/19193873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4411-08.2009
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