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Type I Interferon Induction in Dendritic Cells Requires IRF-8 That Effects the Feedback Phase of Transcription
Dendritic cells (DCs) produce type I interferons (IFNs) in greater amounts than other cells, but the mechanisms remain elusive. Here we studied the role of a transcription factor, IRF-8 in DC induction of type I IFNs. Upon NDV infection, bone marrow derived plasmacytoid and conventional DCs induced...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2768351/ https://ncbi.nlm.nih.gov/pubmed/17702615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2007.06.009 |
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