Dissociation Between Fatty Liver and Insulin Resistance in Humans Carrying a Variant of the Patatin-Like Phospholipase 3 Gene

OBJECTIVE: In a genome-wide association scan, the rs738409 C>G single nucleotide polymorphism (SNP) in the patatin-like phospholipase 3 gene (PNPLA3) was strongly associated with increased liver fat but not with insulin resistance estimated from fasting values. We investigated whether the SNP det...

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Main Authors: Kantartzis, Konstantinos, Peter, Andreas, Machicao, Fausto, Machann, Jürgen, Wagner, Silvia, Königsrainer, Ingmar, Königsrainer, Alfred, Schick, Fritz, Fritsche, Andreas, Häring, Hans-Ulrich, Stefan, Norbert
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2009
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768178/
https://ncbi.nlm.nih.gov/pubmed/19651814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0279
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