SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention – the TULIP Study

BACKGROUND: Sirtuin1 (SIRT1) regulates gene expression in distinct metabolic pathways and mediates beneficial effects of caloric restriction in animal models. In humans, SIRT1 genetic variants associate with fasting energy expenditure. To investigate the relevance of SIRT1 for human metabolism and c...

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Hauptverfasser: Weyrich, Peter, Machicao, Fausto, Reinhardt, Julia, Machann, Jürgen, Schick, Fritz, Tschritter, Otto, Stefan, Norbert, Fritsche, Andreas, Häring, Hans-Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626584/
https://ncbi.nlm.nih.gov/pubmed/19014491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-100
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