Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle

OBJECTIVE: Insulin resistance is a major characteristic of type 2 diabetes and is causally associated with obesity. Inflammation plays an important role in obesity-associated insulin resistance, but the underlying mechanism remains unclear. Interleukin (IL)-10 is an anti-inflammatory cytokine with l...

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Main Authors: Hong, Eun-Gyoung, Ko, Hwi Jin, Cho, You-Ree, Kim, Hyo-Jeong, Ma, Zhexi, Yu, Tim Y., Friedline, Randall H., Kurt-Jones, Evelyn, Finberg, Robert, Fischer, Matthew A., Granger, Erica L., Norbury, Christopher C., Hauschka, Stephen D., Philbrick, William M., Lee, Chun-Geun, Elias, Jack A., Kim, Jason K.
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2009
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768157/
https://ncbi.nlm.nih.gov/pubmed/19690064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db08-1261
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