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Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver

Stearoyl-CoA desaturase 1 (SCD1), a lipogenic enzyme that adds a double bond at the delta 9 position of stearate (C18: 0) and palmitate (C16: 0), has been proven to be important in the development of obesity. Mice with skin-specific deficiency of SCD1 (SKO) display increased whole-body energy expend...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Dumas, Sabrina N, Guo, Chang-an, Kim, Jason K., Friedline, Randall H., Ntambi, James M
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309575/
https://ncbi.nlm.nih.gov/pubmed/30470572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2018.11.083
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