Effects of VEGFR-3 phosphorylation inhibitor on lymph node metastasis in an orthotopic diffuse-type gastric carcinoma model

BACKGROUND: Vascular endothelial growth factor receptor-3 (VEGFR-3) signalling mediates lymphangiogenesis and lymphatic invasion; however, the effect of VEGFR-3 inhibition on the lymph node (LN) metastasis remains unclear. The aim of this study is to clarify the benefit of a VEGFR-3 inhibitor Ki2305...

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Hlavní autoři: Yashiro, M, Shinto, O, Nakamura, K, Tendo, M, Matsuoka, T, Matsuzaki, T, Kaizaki, R, Ohira, M, Miwa, A, Hirakawa, K
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2009
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2768106/
https://ncbi.nlm.nih.gov/pubmed/19738610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605296
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