OXIDATIVE EPITHELIAL HOST DEFENSE IS REGULATED BY INFECTIOUS AND INFLAMMATORY STIMULI

Epithelia express oxidative anti-microbial protection that uses lactoperoxidase (LPO), hydrogen peroxide (H(2)O(2)) and thiocyanate to generate the reactive hypothiocyanite. Duox1 and Duox2, found in epithelia, are hypothesized to provide H(2)O(2) for use by the LPO. To investigate regulation of oxi...

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Autores principales: Gattas, Monica Valencia, Forteza, Radia, Fragoso, Miryam A., Fregien, Nevis, Salas, Pedro, Salathe, Matthias, Conner, Gregory E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767478/
https://ncbi.nlm.nih.gov/pubmed/19703552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.08.017
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