The Lactoperoxidase System Links Anion Transport To Host Defense in Cystic Fibrosis

Chronic respiratory infections in cystic fibrosis result from CFTR channel mutations but how these impair antibacterial defense is less clear. Airway host defense depends on lactoperoxidase (LPO) that requires thiocyanate (SCN(−)) to function and epithelia use CFTR to concentrate SCN(−) at the apica...

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Detaylı Bibliyografya
Asıl Yazarlar: Conner, Gregory E., Wijkstrom-Frei, Corinne, Randell, Scott H., Fernandez, Vania E., Salathe, Matthias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2006
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851694/
https://ncbi.nlm.nih.gov/pubmed/17204267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2006.12.025
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